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A systematic review and meta-analysis of the epidemiology of BVDV infection in dairy cattle in China

Xuhua Rana1, Xiaohong Chena,1, Lili Maa,1, Xiaobo Wena, Junjun Zhaia, Miaomiao Wanga, Xiaodan Tonga, Guangyu Houb, Hongbo Nia

  • College of Animal Science & Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province, 163319, China

    College of Basic Medicine, Mudanjiang Medical College, Mudanjiang, Heilongjiang Province, 157011, China


In this systematic review and meta-analysis, it was validated that the BVDV infection in dairy herds was widely distributed throughout China and the total prevalence was 53.0% between 2003–2018. The BVDV prevalence based on this analysis is comparable to epidemiological data in Asia (Uddin et al., 2017), Africa, (Aragaw et al., 2018), Europe (Mockeliuniene et al., 2004; Mawhinney et al., 2007), Latin America (Saa et al., 2012) and elsewhere (Shirvani et al., 2012) with reported seroprevalence ranging between 11.1% and 100%. As vaccination against BVDV with commercial vaccines is not practical in China before 2018, the presence of BVDV-specific antibodies indicates a natural exposure of cattle to wild BVDV.