In this systematic review and meta-analysis, it was validated that the BVDV infection in dairy herds was widely distributed throughout China and the total prevalence was 53.0% between 2003–2018. The BVDV prevalence based on this analysis is comparable to epidemiological data in Asia (Uddin et al., 2017), Africa, (Aragaw et al., 2018), Europe (Mockeliuniene et al., 2004; Mawhinney et al., 2007), Latin America (Saa et al., 2012) and elsewhere (Shirvani et al., 2012) with reported seroprevalence ranging between 11.1% and 100%. As vaccination against BVDV with commercial vaccines is not practical in China before 2018, the presence of BVDV-specific antibodies indicates a natural exposure of cattle to wild BVDV.